One-pot synthesis of difluoromethyl ketones by a difluorination/fragmentation process.
نویسندگان
چکیده
Difluoromethyl ketones are an under-studied class of ketones which have great potential as useful building blocks for materials and drug design. Here we report a simple and convenient synthesis of this class of compounds via a one-pot difluorination/fragmentation of 1-trifluoromethyl-1,3-diketones which should now allow the chemistry of difluoromethyl ketones to be fully developed.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 14 5 شماره
صفحات -
تاریخ انتشار 2016